Comparison of the Effectiveness of Magnesium Sulphate with Glycerine and Heparinoid Ointment Application on Phlebitis. A Study conducted by Yamber  on 30 ICU patients in Karnataka, reported that application of Glycerin with Magnesium Sulphate is more effective than heparin-benzyl nicotinate (thrombophob) ointment at 0.05 level of significant (t = 2.301) on management of cannula induced thrombophlebitis. Home delivery services for glycerine + magnesium sulphate may be free or they may cost you depending on the pharmacy and the minimum order requirements. Table 6 demonstrates that there is a statistically significant difference in VIP score among the participants in magnesium sulphate with glycerin group and heparinoid ointment groups after each intervention (P < 0.05). • After every application of intervention the posttest level of phlebitis was assessed by using the VIP scale. Comparision of the effectiveness of magnesium sulphate with glycerine and heparinoid ointment application on phlebitis (n = 50). Questionnaire and observation were used to collect the data regarding the prevalence of phlebitis and the effective management measure for phlebitis. However, our data did not provide sufficient statistical evidence to prove and validate this result. Phlebitis is the inflammation of the tunica intima of the vein. • Both procedure were repeated 3 times a day at interval of 8 hours continuously for 2 days. ).Some health conditions may make you more susceptible to the side-effects of the drug. Similarly, a study conducted in KU Nepal by Singh  found very mild (40%) and mild (11.3%) grades were seen to the higher than moderate (3.9%) and severe (3.9%) phlebitis. Monitoring: Data was taken and sequential coding was done. So research hypothesis was accepted. Magnesium Sulphate Dressing. But the association was not statistically significant. Discussion: In the research study findings revealed that Glycerin Magnesium sulphate dressing is highly effective in decrease phlebitis level to the patients. Small size catheters allow more blood flow in adjacent tissues and thereby prevent damage to the tunica intima of the vein. Purpose of intravenous cannula in the participants (n = 50). In this study, the instruments baseline performa and observation scale were used. Listing a study does not mean it has been evaluated by the U.S. Federal Government. It shows that there is more reduction of VIP score in MSG group. Types of illness, days of hospital stay, cannula insertion site, size of cannula and frequency of insertion shows no statistical significance so both groups are homogenously significant with P-value of (0.05). Confidentiality and anonymity were maintained by writing code number instead of name of participants. Similarly another study conducted by Zhao  also proved that the topical application of glycerin magnesium sulphate was safe, simple and effective method with many advantages in phlebitis management. This study found that cannula of 16 G, 18 G and 20 G predicts more than 22 G cannula among both groups the most common catheter used was size ≤ 20 G which was approximately eighty percentage i.e. Children < 6 years: Insert 1 infant suppository 1-2 times daily as needed. Patients have VIP score 2 or above were only as study samples. 2007;33(2):67-69. 38 (76%) out of them majority of 21 (84%) and 17 (68%) of the respondents were cannulated with ≤ 20 G cannula in HPA and MSG group respectively. Table 4 depicts that majority of 16% and 80% participants had pain along the pathway in MSG and HPA groups. Thus it was concluded that both the applications were effective in reducing level of phlebitis. Glycerin, also called glycerol, can be used for both cosmetic purposes and as a treatment for medical conditions of the skin. The result is an alcohol-based product that is an ingredient in many skin-care products. However this finding is contradictory to the finding of other studies. Similarly few were under blood transfusion and in NPO/unconscious. Types of illness, days of hospital stay, cannula insertion site, size of cannula and frequency of insertion shows no statistical significance so both groups are homogenously significant with P-value of (0.05). A significant number of patients admitted into hospital receive some forms of intravenous therapy through peripheral venous cannula, which is a common procedure carried out in hospital Dr. Bruce Jacobs answered. According to age in years maximum numbers of the participants 30% were from the age group of 46 - 65 years in both MSG as well as HPA group. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for glycerine + magnesium sulphate and other medicines and health products. Materials and Methods The average score has been reduced on post-test score in both groups. Likewise a study found out the most effective applicant for reduction of phlebitis in comparison of Heparinoid and Ichthammol glycerine. Magnesium Sulphate with Glycerin dressing and Heparinoid ointment application are found to be used widely for the management of phlebitis. It is composed of three carbon atoms, five hydrogen atoms, and three hydroxy or OH groups . Heparin also has an antiphlogistic and anti-exudative effect, thus alleviating pain and promoting tissue metabolism and the process of healing . Possible side effects Association of Socio-Demographic Variables and Severity Score. Swelling was observed in 72% and 88% in MSG and HPA groups respectively. Effectiveness of Magnesium Sulphate with Glycerin and Heparinoid Ointment Application on Phlebitis. A study conducted by Wallis, Singh   established larger catheter size ≤ 20 G (18 or smaller gauze) predicts phlebitis. Background: Cellulitis is an acute inflammatory condition of the skin that is characterized by localized pain, erythema, swelling and heat. According to licensed acupuncturist Duane Law, Epsom salt can even be used to treat open wounds. Table 7 Demonstrate that there is a statistically significant difference in phlebitis score in both experimental groups MSG and HPA groups after comparison baseline within 8, 16, 32, 40, 48 hours of administration of intervention (P = 0.05). However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. Some of the brands for glycerine + magnesium sulphate might be better known than glycerine + magnesium sulphate itself. 25 participants in Group B (application of Heparinoid ointment). Rinse with cold water. Suppose you want to make 1 table spoon of paste. So, the difference between pre and post-score was found. Similarly, there was no significant association between magnesium sulphate with glycerin dressing and heparinoid ointment application on management of phlebitis with selected socio-demographic variables and cannula related factors. A set of interventions should be established to ensure that an enabling environment is created for the use of the recommendations (including, for example, the availability of magnesium sulfate and calcium gluconate), and that the behaviour of the healthcare practitioner changes towards the use of this evidence-based practice. Methods: This study comprises of Socio-demographic characteristics of the participants (n = 50). Regarding insertion site, the present study found that the most common location for insertion of cannula was in wrist 34% followed by Dorsum of hand 30% among both groups among them the least 14% was forearm; 22% was reported in the cubital fossa. Thus it was concluded that both the applications were effective in reducing level of phlebitis. However there are no more studies to support this finding. If the pharmacy that's willing to deliver medicines to your home doesn't have glycerine + magnesium sulphate in stock, you can ask for one of the branded alternatives for glycerine + magnesium sulphate. It is becoming a common practice in hospitals. The mean VIP score is more in MSG group as compared with that of HPA group. ), allergies, pre-existing diseases, and current health conditions (e.g. a = Mann-Whitney U Test; b = Kruskal Wallis Test. Most 38 (76%) of the participants were cannulated with less than and equal to 20 G cannula Frequency of cannula insertion was more than and equal to second time of nearly 90% among both groups. Cellulitis may be caused by indigenous flora colonies of the skin appendages. Multiple factors, related to the catheter itself or the solution infused have been associated with this common complication . For use on the skin only. pregnancy, upcoming surgery, etc. Descriptive statistics such as mean, standard deviation, rank were used to present socio-demographical, health-related, cannula and infusion-related variables. a = Mann-Whitney U Test, b = Kruskal Wallis test. So it is revealed that Magnesium Suphate with Glycerin is more effective than Heparinoid ointment in management of phlebitis. A study conducted by Singh, on 230 admitted clients in Dhulikhel Teaching Hospital Nepal resulted that in 59.1% development of phlebitis mostly very mild in nature. Patel Krupa D (2015) evaluate effectiveness to of glycerin magnesium sulphate dressing on phlebitis among patients undergoing peripheral intravenous infusion.In the research study, findings revealed that Glycerin Magnesium sulphate dressing is highly effective in decrease phlebitis level to the patients.4 3. For use on the skin only. Glycerine + Magnesium Sulphate is a generic medicine name and there are several brands available for it. If swallowed: Talk to a pharmacist or doctor. Gently massage your face with the paste mixed with your cleansing cream. Patients who were not willing to participate and were under cytitoxic drugs were excluded in research. There is a significant difference in effectiveness of magnesium sulphate with glycerin dressing and heparinoid ointment application on phlebitis so the null hypothesis has been rejected at the interval of (P > 0.05). • To evaluate the effectiveness of Magnesium sulphate with glycerin dressing versus Heparinoid ointment application on management of peripheral cannula induced phlebitis. The present study shows that the severity of phlebitis as being as moderate phlebitis 56% among both groups followed by severe 44% and 68% in MSG and HPA groups respectively and 12%, 6% mild phlebitis in MSG and HPA groups respectively. Visual infusion scale (VIP scale) used for measuring the phlebitis according to score. Table 2 depicts majority of 40 (80%) participants days of hospital stay was below 1 week among both MSG and HPA group, majority about two fifth 10 (40%) of cannula was inserted in wrist in HPA group and equal number of the participants (16%) of cannula was on forearm from both groups and equal (28%) in both dorsum of hand and cubital fossa in MSG group. Adults and children > 6 years: Insert 1 suppository; high in the rectum and retain for 15 minutes. This finding of the study is being supported by the study conducted Yamber  on 30 ICU patients in Karnataka, which showed the difference between pre and post score was found to be significant. The main ingredient in Epsom salt is magnesium, which is "the second-most abundant element in human cells and the fourth-most important positively charged ion in the body," according to the Epsom Salt Council 1. On post-test score in MSG group and control group regularly talk to a pharmacist or doctor ½ cup of water. 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